Automated organelle-based colocalization in whole-cell imaging

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Whole-Genome Hitchhiking on an Organelle Mutation

Strong selection on a beneficial mutation can cause a selective sweep, which fixes the mutation in the population and reduces the genetic variation in the region flanking the mutation [1-3]. These flanking regions have increased in frequency due to their physical association with the selected loci, a phenomenon called "genetic hitchhiking" [4]. Theoretically, selection could extend the hitchhik...

متن کامل

Automated Whole Animal Bio-Imaging Assay for Human Cancer Dissemination

A quantitative bio-imaging platform is developed for analysis of human cancer dissemination in a short-term vertebrate xenotransplantation assay. Six days after implantation of cancer cells in zebrafish embryos, automated imaging in 96 well plates coupled to image analysis algorithms quantifies spreading throughout the host. Findings in this model correlate with behavior in long-term rodent xen...

متن کامل

An Automated Blur Detection Method for Histological Whole Slide Imaging

Whole slide scanners are novel devices that enable high-resolution imaging of an entire histological slide. Furthermore, the imaging is achieved in only a few minutes, which enables image rendering of large-scale studies involving multiple immunohistochemistry biomarkers. Although whole slide imaging has improved considerably, locally poor focusing causes blurred regions of the image. These art...

متن کامل

Mitochondria Organelle Transplantation: The Mitochondrion, “An Intracellular Organelle for Cell-Based Therapy” Opinion Commentary

Mitochondria are powerful intracellular organelles involved in many vital cellular functions especially cellular respiration and energy production. Mitochondrial dysfunction is associated with many human diseases including cancer and neurodegenerative disease. Warburg showed in the 1920s that defective mitochondrial respiration altered tumor cell metabolism with a shift to glycolysis, an initia...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Cytometry Part A

سال: 2009

ISSN: 1552-4922,1552-4930

DOI: 10.1002/cyto.a.20786